Eliminate Wrinkles While you Sleep


Heather Locklear attributes her unlined appearance to being a “back sleeper.” Dermatologists recommend that you don’t sleep on your face to avoid wrinkles.


What’s a girl to do? Buy this copper-powered pillowcase from Cupron, who pioneered the use of the mineral in products. It’s made from a luxurious satin but the best part is seeing a subtle difference even after just a week of sleeping on it! Plus it’s anti-microbial; great for people with allergies.

Originally a medical research company, with many patents in the use of copper oxide, after 10 years of research they discovered it also had many consumer applications such as with the wrinkles and body-odor. Many people know them for their deodorant copper sole socks which fight against foot-odor-causing bacteria and fungi the special Cupron fibers eliminate 99.9% of the growth of foot-odor-causing bacteria and fungi that were tested, for the life of the sock. ($11.99 for men’s socks.)

We wondered if the beneficial properties would wear out after repeated washings but the company explained that the “biocidal properties of cupronized fabrics are permanent.” One caveat, don’t use fabric softeners for your copper socks, towels, bedding etc.

At $37 for the pillowcase, we consider it one of the best investments we’ve ever made.  Right now, it’s on sale for the holidays for only $28.99!

Slow Down the Aging Process Now With All-Natural Solutions!

If you're in your 40s, 50s, 60s or 70s... you may be experiencing heart problems, joint pain, blood sugar imbalance, vision problems, memory loss or muscle fatigue. Your doctor may have chalked these symptoms up to "old-age". And just like millions of Americans, you may have turned to dangerous prescription drugs or risky surgical procedures to help slow down the effects of aging. But, medical science has now shown that many of these health problems can be improved and may even be able to be REVERSED...
One of the main causes of aging is free radical damage. These rogue molecules can lead to dozens of health problems. By controlling free radical damage, you can help slow down aging... help prevent illness... and protect your body's energy storehouse.
Block DNA and RNA function—DNA is the "blueprint" that tells your cells how to act... duplicate... and even how to repair itself. RNA transmits the information in the DNA to your cells. Free radicals can damage both DNA and RNA communication—causing your cells to malfunction and even self-destruct.Plus, free radical damage can also:
  • Release dangerous cholesterol in your bloodstream—When fat molecules such as cholesterol get oxidized, they become sticky. That means they can clog up your arteries and set the stage for future heart and brain problems.
  • Quickly drain your energy—Free radicals release a toxic waste matter called lipofuscins. This yellowish-brown cell debris can interfere with your body's ability to metabolize protein—your #1 source of energy.
  • Trigger joint pain and muscle aches—An overproduction of free radicals in a specific area can cause inflammation.
  • Prematurely age your skin—Free radicals destroy delicate collagen that keeps your skin soft, smooth and flexible. If you've got age spots on your hands or face, that's a tell-tale sign you've got free radical damage.
The truth is you can't get away from free radicals. The very process of breathing creates these destructive molecules. What's more, foods... environmental pollutants... toxins... and even stress can trigger "hits" from free radicals.
Fortunately, Mother Nature gives us remarkably safe and effective solutions to help clobber pesky free radicals. They're called antioxidants:
  • Phosphatidylserine (PS for short)—proven incredibly effective for age-related memory loss in 60 human studies and over 2,800 scientific papers... PS helps restore a more youthful memory and helps sharpen thinking and reasoning ability...
  • Vinpocetine is natures powerful memory enhancer that works by expanding your blood vessels to allow healthy blood flow to the brain and gingko biloba helps boost memory, improve concentration and fight off mental fatigue...
  • Omega-3 is the powerful anti-inflammatory oil that helps lubricate your brain cells to keep them working at peak capacity and DMAE can help scrape away and remove harmful lipofuscins that cause brain "rust"....
  • Folic acid—helps protect your veins, arteries and capillaries supplying blood to your brain and your entire body...
  • CDP choline—is one of the basic building blocks for brain function...
  • Acetyl-L-carnitine—helps boost energy levels to your entire body...
  • Alpha lipoic acid, L-glutathione, vitamin C and
    vitamin E
    —these antioxidants help "switch off" faulty DNA before it can trigger health problems...
  • Plus, quercetin, selenium, hesperidin and RNA—boost memory recall and brain function... reduce damage from stress... allow your brain cells to "talk" to one another more effectively... and slow your total body aging to a crawl.
By adding these and other powerful antioxidants to your daily regimen, you can expect to feel and look younger for decades to come!

Original article by Dr. Cutler 

How Lack Of Sleep Can Effect How You Age and what you can do about it

Lack of sleep doesn't just affect your energy levels, concentration and focus through out the day. It has been shown in many studies like the  University of Chicago one that it actually alters hormones and metabolism as well which simulate effects of aging.


They found that cutting back from the standard eight down to four hours of sleep each night produced striking changes in glucose tolerance and endocrine function--changes that resembled the effects of advanced age or the early stages of diabetes--after less than one week.

Most of these studies are only done on short term effects but no none really knows how will effect you over the long term. Although some research has speculated that it increases the risks for heart disease, high blood pressure and other related medical conditions. Especially if someone is exposed to chronic sleep disruptions.

With that being said what can we do about it. Ive compiled some tips to help you get some more ZZZZZZ's

The recommended sleep requirement for adults is between 7-9 hours a night. However, each person is different and it may change throughout their life.


The following tips will help any individual achieve a great night's sleep and feel rejuvenated for a new day:
  • Stick to a sleep schedule: Try to go to bed and wake up at the same time each day.
  • Avoid caffeine and nicotine: The stimulating effects of these products can prevent a sufficient night's sleep.
  • No midnight snacking: The stimulating effects of these products can prevent a sufficient night's sleep.
  • Sleeping Environment: The best sleeping environment is somewhere: dark, quiet, cool (67-68 degrees), with a comfortable sleeping surface and privacy (closed door/shut blinds).
Overall, proper sleeping habits are required in order for us to maintain good health and keep us functioning at our very best! 



Anti-Aging Drug Breakthrough


Drugs that combat aging may be available within five years. 
Four thousand synthetic activators, which are 100 times as 
potent as a single glass of red wine, have been developed -- 
the best three are in human trials. (Credit: © vgstudio / Fotolia)
Mar. 8, 2013 — Drugs that combat aging may be available within five years, following landmark work led by an Australian researcher.




The work, published in the March 8 issue of Science, finally proves that a single anti-aging enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.
The paper shows all of the 117 drugs tested work on the single enzyme through a common mechanism. This means that a whole new class of anti-aging drugs is now viable, which could ultimately prevent cancer, Alzheimer's disease and type 2 diabetes.
"Ultimately, these drugs would treat one disease, but unlike drugs of today, they would prevent 20 others," says the lead author of the paper, Professor David Sinclair, from UNSW Medicine, who is based at Harvard University. "In effect, they would slow aging."
The target enzyme, SIRT1, is switched on naturally by calorie restriction and exercise, but it can also be enhanced through activators. The most common naturally-occurring activator is resveratrol, which is found in small quantities in red wine, but synthetic activators with much stronger activity are already being developed.
Although research surrounding resveratrol has been going for a decade, until now the basic science had been contested. Despite this, there have already been promising results in some trials with implications for cancer, cardiovascular disease and cardiac failure, type 2 diabetes, Alzheimer's and Parkinson's diseases, fatty liver disease, cataracts, osteoporosis, muscle wasting, sleep disorders and inflammatory diseases such as psoriasis, arthritis and colitis (inflammatory bowel disease).
"In the history of pharmaceuticals, there has never been a drug that tweaks an enzyme to make it run faster," says Professor Sinclair, a geneticist with the Department of Pharmacology at UNSW.
The technology was sold to pharmaceutical giant GlaxoSmithKline in 2008[i]. Four thousand synthetic activators, which are 100 times as potent as a single glass of red wine, have been developed -- the best three are in human trials.
"Our drugs can mimic the benefits of diet and exercise, but there is no impact on weight," says Professor Sinclair, who suggests the first therapeutic to be marketed will be for diabetes.
There have been limited trials in people with type 2 diabetes and the skin inflammatory disease, psoriasis. There were benefits to the metabolism in the first group and a reduction in skin redness in the second.
The drugs can be administered orally, or topically. So far, there have been no drugs developed targeting aging skin, but one major skin care range has developed a crème with resveratrol in it.
While any drug would be strictly prescribed for certain conditions, Professor Sinclair suggests that one day, they could be taken orally as a preventative. This would be in much the same way as statin drugs are commonly prescribed to prevent, instead of simply treating, cardiovascular disease.
In animal models, overweight mice given synthetic resveratrol were able to run twice as far as slim mice and they lived 15 per cent longer.
"Now we are looking at whether there are benefits for those who are already healthy. Things there are also looking promising," says Professor Sinclair, who also heads the Lowy Cancer Research Centre's Laboratory for aging Research at UNSW.
"We're finding that aging isn't the irreversible affliction that we thought it was," he says. "Some of us could live to 150, but we won't get there without more research."
[i] Professor Sinclair formed a started up company Sirtris to develop the anti-aging technology. This was subsequently sold to GlaxoSmithKline (GSK). Professor Sinclair is now a scientific advisor to GSK. Several other authors on the paper work for GSK or an affiliated company.

The above story is reprinted from materials provided by University of New South Wales.


LifeExtension Earns Top Rating in CL Survey

FORT LAUDERDALE, Fla..—Dietary supplement consumers rated Life Extension first in three categories in the 2013 ConsumerLab.com Survey of Vitamin and Supplement users. Life Extension received top ratings in the CoQ10 and multivitamin products and, for the second year in a row, was rated No. 1 catalog/internet supplement brand. Nearly 11,000 supplement users participated in the survey.

"We endeavor to formulate and produce the finest quality products backed by science and are proud of our online and catalog offerings and customer service," said Paul Gilner, Life Extension CEO. "We're thrilled consumers rated us number one again in those three categories."

LifeExtension offers more than 350 supplement products, including its popular CoQ10. Learn more about challenges in the brain-boosting CoQ10 industry in the INSIDER slide show "Creating CoQ10 Products."

If you are not familiar with the benefits CoQ10 can have on your brain function check out this article from teh LiveStrong Foundation.

Telomerase Research and Current Products on the Market

Telomerase Background
Telomere's in red at end of chromosomes
The HeLa cell line was derived for use in cancer research. These cells proliferate abnormally rapidly, even compared to other cancer cells. Like many other cancer cells, HeLa cells have an active version of telomerase during cell division, which prevents the incremental shortening of telomeres that is implicated in aging and eventual cell death. In this way the cells circumvent the Hayflick Limit, which is the limited number of cell divisions that most normal cells can later undergo before becoming senescent(cell death).

Current Research

The journal Nature published a fascinating study about the enzyme’s effect on genetically engineered mice last year. In the study, researchers bred mice that, in normal conditions, didn’t create telomerase. The mice grew to adulthood without the enzyme. Then, for a month, the team provided the mice with a trigger chemical that allowed the mice to create telomerase.

Without the telomerase, the researchers discovered that the mice tend to age prematurely. They contracted osteoporosis or diabetes, and they tended to die earlier than normal mice. Then, during their month with telomerase, things turned around.

Sterile animals became fertile again. Prematurely aged internal organs returned to health. Telomerase also reversed aging’s effects in the mouse’s brains.

Other cutting edge research on telomerase shown to extend telomeres length longer than usual

Products On the Market Now
1.TA sciences and ta-65 telomerase shortening supplements
October 2010, Intertek/AAC Labs, an ISO 17025 internationally recognized lab, found the largest component of TA-65 to be Cycloastragenol
600$ per 3 months supply at TA Sciences

2.Alternative that may work is  Cycloastragenol supplements  1-2months supply for 300$

3.Astragulus directly from the root where the ta-65 extract came from. If you go this route be careful as Astragulus root has been shown to suppress the immune system or even be toxic in some species of this plant.

Warnings

Some precautions before trying these supplements. Since this is new research there is always the possibility of unknown side effects over longer term usage. Telomerase is produced in cancer cells so it is possible that telomerase may support existing cancer cells. Of course this is only theoretical

Telomerase shortening does not occur the same way in animals as humans making it very difficult to test the viability of telomerase preserving products.

Proven Therapies
To date altering your lifestyle to live longer has been proven to be effective in many parts of the world. Dan Buettner's Blue Zones book explores cultures around the world that live longer on average by 10-20 years than that of the majority of westerners. Places like Ikaria Greece, the Swedish town of Kungsholmen, Okinawa, Japan and Nicoya in Costa Rica show that maintaining active social networks, pursuing leisure activities, avoiding smoking, getting regular exercise, eating lots of vegetables and fruit, a little fish and whole grains and a little red wine is their secret to longevity. Some scientists have speculated that these people are increasing telomerase activity already naturally.

Further Reading
Dan Buettner's The Blue Zones
Workbook for the Blue Zones Thrive: Finding Happiness the Blue Zones Way

The Paleo Diet

Recently I started learning about the Paleo elimination diet. Its basically about how our bodies evolved over millions of years by eating specific types of natural foods. These days obesity and diabetes is becoming an epidemic. Why? Diabetes is usually blamed on poor eating of too much sugary foods but grains produce the same insulin spike as sugars do since starches are metabolized into sugars. So why aren't grains on this list? The Paleo Solution asks these questions.

I am looking for more clinical data on grain heavy diets and how they affect our health.I have been unable to find any clinical data or studies done on grain heavy diets. High starch vegetable diets however seem to be unhealthy for you as the starches are converted in sugar in the body which is nearly the same.

The majority of the information in the book I found to be very convincing  and overall his theory seems sound. I completely agree with his advice on eating a large amount of vegetables and fruit,nuts with lean protein sources,low sugar intake and plenty of exercise. There are many other studies like The China Study that have been done that have proven this. See "The China Study"

Unfortunately there are many statements by the author on what constitutes healthy fats like flax oil and vegetable oils to be very inaccurate. The authors a stance on a very low salt diet has been proven to be true as high salt diets have been shown to be a factor in high blood pressure but i felt he was doing a little too much scaremongering. Some other advice like you can't eat too much protein is just plain wrong and

Overall a quick read with a plan for you to take action on the information within the book. Its hard to go wrong with this book
The Paleo Solution: The Original Human Diet

The China Study: The Most Comprehensive Study of Nutrition Ever Conducted And the Startling Implications for Diet, Weight Loss, And Long-term Health

Life-Extension-The future is now

Have you ever had a profound life altering experience?

I had one 3 years ago when i watched this video. The experience came when i seriously asked myself
"Do i want to live forever?".


This video is a little long at 1hr 16mins but its well worth your time.
If you are seriously interested in anti aging you need to get involved.

You can start by signing up for our 100% free e-report on superfoods that have anti-aging properties. In the near future i will be providing as much free information, materials and resources that i can get my hands on to be available for people that are interested in being proactive.

Jason McDonald
Senior editor

How to lose 50 years of aging in 16 days

Gold nanoparticles darken white hair after treatment for one day, 
center, and 16 days, right (credit: American Chemical Society)
Attention seniors: French scientists have developed a process that permanently dyes white hair without harmful chemicals.

Philippe Walter and colleagues soaked white hairs in a solution containing fluorescent gold nanoparticles.

The hairs turned pale yellow and then darkened to a deep brown. The color remained even after repeated washings.

Using an electron microscope, the scientists confirmed that the particles were forming inside the hairs’ central core cortex.
The discovery has applications ranging from hair dyeing to electronic sensors to development of materials with improved properties, the scientists said.
The synthesis and detailed characterization of gold nanoparticles (AuNPs) inside human hair has been achieved by treatment of hair with HAuCl4 in alkaline medium. The AuNPs, which show a strong red fluorescence under blue light, are generated inside the fiber and are arranged in the cortex in a remarkably regular pattern of whorls based on concentric circles, like a fingerprint. It opens an area of genuine nanocomposites with novel properties due to AuNPs inside the hair shaft. (Credit: American Chemical Society)  
Article by Kurzweilai.net